Serotonergic system antagonists target breast tumor initiating cells and synergize with chemotherapy to shrink human breast tumor xenografts

Breast tumors comprise an infrequent tumor cell population, termed breast tumor initiating cells (BTIC), which sustain tumor growth, seed metastases and resist cytotoxic therapies. Hence therapies are needed to target BTIC to provide more durable breast cancer remissions than are currently achieved....

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Detalles Bibliográficos
Autores principales: Gwynne, William D, Hallett, Robin M, Girgis-Gabardo, Adele, Bojovic, Bojana, Dvorkin-Gheva, Anna, Aarts, Craig, Dias, Kay, Bane, Anita, Hassell, John A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458271/
https://www.ncbi.nlm.nih.gov/pubmed/28404880
http://dx.doi.org/10.18632/oncotarget.16646

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