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Targeting HOX/PBX dimers in cancer

The HOX and PBX gene families encode transcription factors that have key roles in establishing the identity of cells and tissues in early development. Over the last 20 years it has become apparent that they are also dysregulated in a wide range of solid and haematological malignancies and have a pre...

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Detalles Bibliográficos
Autores principales: Morgan, Richard, El-Tanani, Mohamed, Hunter, Keith D., Harrington, Kevin J., Pandha, Hardev S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458287/
https://www.ncbi.nlm.nih.gov/pubmed/28423659
http://dx.doi.org/10.18632/oncotarget.15971