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IGFBP2 Produces Rapid-Acting and Long-Lasting Effects in Rat Models of Posttraumatic Stress Disorder via a Novel Mechanism Associated with Structural Plasticity
BACKGROUND: Posttraumatic stress disorder is an anxiety disorder characterized by deficits in the extinction of aversive memories. Insulin-like growth factor 1 (IGF1) is the only growth factor that has shown anxiolytic and antidepressant properties in human clinical trials. In animal studies, insuli...
Autores principales: | Burgdorf, Jeffrey, Colechio, Elizabeth M., Ghoreishi-Haack, Nayereh, Gross, Amanda L., Rex, Christopher S., Zhang, Xiao-lei, Stanton, Patric K., Kroes, Roger A., Moskal, Joseph R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458343/ https://www.ncbi.nlm.nih.gov/pubmed/28158790 http://dx.doi.org/10.1093/ijnp/pyx007 |
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