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AMP‐activated protein kinase regulates lipid metabolism and the fibrotic phenotype of hepatic stellate cells through inhibition of autophagy

Hepatic stellate cells (HSCs) are the principal hepatic cell type responsible for liver fibrosis. Although AMP‐activated protein kinase (AMPK) is known to regulate the activation of HSCs, little is known about its underlying molecular mechanisms. In the present study, we demonstrate that AMPK activa...

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Detalles Bibliográficos
Autores principales: Chen, Ming, Liu, Jiaxing, Yang, Lili, Ling, Wenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458462/
https://www.ncbi.nlm.nih.gov/pubmed/28593136
http://dx.doi.org/10.1002/2211-5463.12221

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