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Licochalcone A specifically induces cell death in glioma stem cells via mitochondrial dysfunction
Glioblastoma multiforme is the most malignant primary intrinsic brain tumor. Glioma stem cells (GSCs) are associated with chemoradiotherapy resistance and the recurrence of glioblastomas after conventional therapy. The targeting of GSCs is potentially an effective treatment for the long‐term surviva...
Autores principales: | Kuramoto, Kenta, Suzuki, Shuhei, Sakaki, Hirotsugu, Takeda, Hiroyuki, Sanomachi, Tomomi, Seino, Shizuka, Narita, Yoshitaka, Kayama, Takamasa, Kitanaka, Chifumi, Okada, Masashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458486/ https://www.ncbi.nlm.nih.gov/pubmed/28593138 http://dx.doi.org/10.1002/2211-5463.12226 |
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