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Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration

Following uncontrolled proliferation, a subset of primary tumour cells acquires additional traits/mutations to trigger phenotypic changes that enhance migration and are hypothesized to be the initiators of metastasis. This study reveals an adaptive mechanism that harnesses synergistic paracrine sign...

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Detalles Bibliográficos
Autores principales: Jayatilaka, Hasini, Tyle, Pranay, Chen, Jonathan J., Kwak, Minsuk, Ju, Julia, Kim, Hyun Ji, Lee, Jerry S. H., Wu, Pei-Hsun, Gilkes, Daniele M., Fan, Rong, Wirtz, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458548/
https://www.ncbi.nlm.nih.gov/pubmed/28548090
http://dx.doi.org/10.1038/ncomms15584