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Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration
Following uncontrolled proliferation, a subset of primary tumour cells acquires additional traits/mutations to trigger phenotypic changes that enhance migration and are hypothesized to be the initiators of metastasis. This study reveals an adaptive mechanism that harnesses synergistic paracrine sign...
Autores principales: | Jayatilaka, Hasini, Tyle, Pranay, Chen, Jonathan J., Kwak, Minsuk, Ju, Julia, Kim, Hyun Ji, Lee, Jerry S. H., Wu, Pei-Hsun, Gilkes, Daniele M., Fan, Rong, Wirtz, Denis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458548/ https://www.ncbi.nlm.nih.gov/pubmed/28548090 http://dx.doi.org/10.1038/ncomms15584 |
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