Cargando…

Conformational dynamics of dynamin-like MxA revealed by single-molecule FRET

Human myxovirus resistance protein 1 (MxA) restricts a wide range of viruses and is closely related to the membrane-remodelling GTPase dynamin. The functions of MxA rely on domain rearrangements coupled with GTP hydrolysis cycles. To gain insight into this process, we studied real-time domain dynami...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yang, Zhang, Lei, Graf, Laura, Yu, Bing, Liu, Yue, Kochs, Georg, Zhao, Yongfang, Gao, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458555/
https://www.ncbi.nlm.nih.gov/pubmed/28548099
http://dx.doi.org/10.1038/ncomms15744