The distinct metabolic phenotype of lung squamous cell carcinoma defines selective vulnerability to glycolytic inhibition

Adenocarcinoma (ADC) and squamous cell carcinoma (SqCC) are the two predominant subtypes of non-small cell lung cancer (NSCLC) and are distinct in their histological, molecular and clinical presentation. However, metabolic signatures specific to individual NSCLC subtypes remain unknown. Here, we per...

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Detalles Bibliográficos
Autores principales: Goodwin, Justin, Neugent, Michael L., Lee, Shin Yup, Choe, Joshua H., Choi, Hyunsung, Jenkins, Dana M. R., Ruthenborg, Robin J., Robinson, Maddox W., Jeong, Ji Yun, Wake, Masaki, Abe, Hajime, Takeda, Norihiko, Endo, Hiroko, Inoue, Masahiro, Xuan, Zhenyu, Yoo, Hyuntae, Chen, Min, Ahn, Jung-Mo, Minna, John D., Helke, Kristi L., Singh, Pankaj K., Shackelford, David B., Kim, Jung-whan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458561/
https://www.ncbi.nlm.nih.gov/pubmed/28548087
http://dx.doi.org/10.1038/ncomms15503

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