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Limitations in the use of 18F-FDG PET in the pre-operative staging of gastric cancer: A case series
INTRODUCTION: Positron emission tomography (PET) is a mainstay in the preoperative evaluation of various cancers. In gastric cancer however, its role in the initial staging remains contentious. Presented is a case series of three gastric patients wherein the use of fluorodeoxyglucose (18F-FDG) PET/C...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458643/ https://www.ncbi.nlm.nih.gov/pubmed/28582710 http://dx.doi.org/10.1016/j.ijscr.2017.05.026 |
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author | Fonocho, Ernest Aydin, Nail Reddy, Srini Misra, Subhasis |
author_facet | Fonocho, Ernest Aydin, Nail Reddy, Srini Misra, Subhasis |
author_sort | Fonocho, Ernest |
collection | PubMed |
description | INTRODUCTION: Positron emission tomography (PET) is a mainstay in the preoperative evaluation of various cancers. In gastric cancer however, its role in the initial staging remains contentious. Presented is a case series of three gastric patients wherein the use of fluorodeoxyglucose (18F-FDG) PET/CT (computer tomography) as part of the initial staging was inconsequential to treatment, demonstrating its limited role in the staging of primary gastric cancer. METHODS: We analyzed retrospective data from 12/1/2010 to 10/31/2016 of patient with gastric cancer whose initial staging included a PET/CT. Only patients 18 years and older with gastric and gastro-oesophageal junction cancers were included. The data was derived from a single institution. Management of patients involved both an academic institution and a community practice. RESULTS: Of the three cases reported, an FDG-avid mass with minimal FDG uptake was reported in a single case and no FDG-avid lesion was reported in the other two. Neither of the patients underwent an endoscopic ultrasound for lack of availability. CONCLUSION: While various imaging studies such as endoscopic ultrasound have an established role in the initial staging, the role of FDG-PET is yet to be established and its routine use remains contentious. Based on our clinical experience and review of the literature, we believe FDG-PET/CT imaging is of limited clinical and cost effective value in the initial staging workup of gastric cancer. |
format | Online Article Text |
id | pubmed-5458643 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-54586432017-06-29 Limitations in the use of 18F-FDG PET in the pre-operative staging of gastric cancer: A case series Fonocho, Ernest Aydin, Nail Reddy, Srini Misra, Subhasis Int J Surg Case Rep Case Report INTRODUCTION: Positron emission tomography (PET) is a mainstay in the preoperative evaluation of various cancers. In gastric cancer however, its role in the initial staging remains contentious. Presented is a case series of three gastric patients wherein the use of fluorodeoxyglucose (18F-FDG) PET/CT (computer tomography) as part of the initial staging was inconsequential to treatment, demonstrating its limited role in the staging of primary gastric cancer. METHODS: We analyzed retrospective data from 12/1/2010 to 10/31/2016 of patient with gastric cancer whose initial staging included a PET/CT. Only patients 18 years and older with gastric and gastro-oesophageal junction cancers were included. The data was derived from a single institution. Management of patients involved both an academic institution and a community practice. RESULTS: Of the three cases reported, an FDG-avid mass with minimal FDG uptake was reported in a single case and no FDG-avid lesion was reported in the other two. Neither of the patients underwent an endoscopic ultrasound for lack of availability. CONCLUSION: While various imaging studies such as endoscopic ultrasound have an established role in the initial staging, the role of FDG-PET is yet to be established and its routine use remains contentious. Based on our clinical experience and review of the literature, we believe FDG-PET/CT imaging is of limited clinical and cost effective value in the initial staging workup of gastric cancer. Elsevier 2017-05-26 /pmc/articles/PMC5458643/ /pubmed/28582710 http://dx.doi.org/10.1016/j.ijscr.2017.05.026 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Fonocho, Ernest Aydin, Nail Reddy, Srini Misra, Subhasis Limitations in the use of 18F-FDG PET in the pre-operative staging of gastric cancer: A case series |
title | Limitations in the use of 18F-FDG PET in the pre-operative staging of gastric cancer: A case series |
title_full | Limitations in the use of 18F-FDG PET in the pre-operative staging of gastric cancer: A case series |
title_fullStr | Limitations in the use of 18F-FDG PET in the pre-operative staging of gastric cancer: A case series |
title_full_unstemmed | Limitations in the use of 18F-FDG PET in the pre-operative staging of gastric cancer: A case series |
title_short | Limitations in the use of 18F-FDG PET in the pre-operative staging of gastric cancer: A case series |
title_sort | limitations in the use of 18f-fdg pet in the pre-operative staging of gastric cancer: a case series |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458643/ https://www.ncbi.nlm.nih.gov/pubmed/28582710 http://dx.doi.org/10.1016/j.ijscr.2017.05.026 |
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