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Targeted recombination between homologous chromosomes for precise breeding in tomato
Homologous recombination (HR) between parental chromosomes occurs stochastically. Here, we report on targeted recombination between homologous chromosomes upon somatic induction of DNA double-strand breaks (DSBs) via CRISPR-Cas9. We demonstrate this via a visual and molecular assay whereby DSB induc...
Autores principales: | Filler Hayut, Shdema, Melamed Bessudo, Cathy, Levy, Avraham A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458649/ https://www.ncbi.nlm.nih.gov/pubmed/28548094 http://dx.doi.org/10.1038/ncomms15605 |
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