The NANCI–Nkx2.1 gene duplex buffers Nkx2.1 expression to maintain lung development and homeostasis

A subset of long noncoding RNAs (lncRNAs) is spatially correlated with transcription factors (TFs) across the genome, but how these lncRNA–TF gene duplexes regulate tissue development and homeostasis is unclear. We identified a feedback loop within the NANCI (Nkx2.1-associated noncoding intergenic R...

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Detalles Bibliográficos
Autores principales: Herriges, Michael J., Tischfield, David J., Cui, Zheng, Morley, Michael P., Han, Yumiao, Babu, Apoorva, Li, Su, Lu, MinMin, Cendan, Isis, Garcia, Benjamin A., Anderson, Stewart A., Morrisey, Edward E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458756/
https://www.ncbi.nlm.nih.gov/pubmed/28546511
http://dx.doi.org/10.1101/gad.298018.117

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