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The role of Nrf1 and Nrf2 in the regulation of glutathione and redox dynamics in the developing zebrafish embryo

Redox signaling is important for embryogenesis, guiding pathways that govern processes crucial for embryo patterning, including cell polarization, proliferation, and apoptosis. Exposure to pro-oxidants during this period can be deleterious, resulting in altered physiology, teratogenesis, later-life...

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Detalles Bibliográficos
Autores principales: Sant, Karilyn E., Hansen, Jason M., Williams, Larissa M., Tran, Nancy L., Goldstone, Jared V., Stegeman, John J., Hahn, Mark E., Timme-Laragy, Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458767/
https://www.ncbi.nlm.nih.gov/pubmed/28582729
http://dx.doi.org/10.1016/j.redox.2017.05.023