Cargando…

Ultrasound Elasticity Imaging System with Chirp-Coded Excitation for Assessing Biomechanical Properties of Elasticity Phantom

The biomechanical properties of soft tissues vary with pathological phenomenon. Ultrasound elasticity imaging is a noninvasive method used to analyze the local biomechanical properties of soft tissues in clinical diagnosis. However, the echo signal-to-noise ratio (eSNR) is diminished because of the...

Descripción completa

Detalles Bibliográficos
Autores principales: Chun, Guan-Chun, Chiang, Hsing-Jung, Lin, Kuan-Hung, Li, Chien-Ming, Chen, Pei-Jarn, Chen, Tainsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458841/
https://www.ncbi.nlm.nih.gov/pubmed/28793718
http://dx.doi.org/10.3390/ma8125458
_version_ 1783241834797989888
author Chun, Guan-Chun
Chiang, Hsing-Jung
Lin, Kuan-Hung
Li, Chien-Ming
Chen, Pei-Jarn
Chen, Tainsong
author_facet Chun, Guan-Chun
Chiang, Hsing-Jung
Lin, Kuan-Hung
Li, Chien-Ming
Chen, Pei-Jarn
Chen, Tainsong
author_sort Chun, Guan-Chun
collection PubMed
description The biomechanical properties of soft tissues vary with pathological phenomenon. Ultrasound elasticity imaging is a noninvasive method used to analyze the local biomechanical properties of soft tissues in clinical diagnosis. However, the echo signal-to-noise ratio (eSNR) is diminished because of the attenuation of ultrasonic energy by soft tissues. Therefore, to improve the quality of elastography, the eSNR and depth of ultrasound penetration must be increased using chirp-coded excitation. Moreover, the low axial resolution of ultrasound images generated by a chirp-coded pulse must be increased using an appropriate compression filter. The main aim of this study is to develop an ultrasound elasticity imaging system with chirp-coded excitation using a Tukey window for assessing the biomechanical properties of soft tissues. In this study, we propose an ultrasound elasticity imaging system equipped with a 7.5-MHz single-element transducer and polymethylpentene compression plate to measure strains in soft tissues. Soft tissue strains were analyzed using cross correlation (CC) and absolution difference (AD) algorithms. The optimal parameters of CC and AD algorithms used for the ultrasound elasticity imaging system with chirp-coded excitation were determined by measuring the elastographic signal-to-noise ratio (SNRe) of a homogeneous phantom. Moreover, chirp-coded excitation and short pulse excitation were used to measure the elasticity properties of the phantom. The elastographic qualities of the tissue-mimicking phantom were assessed in terms of Young’s modulus and elastographic contrast-to-noise ratio (CNRe). The results show that the developed ultrasound elasticity imaging system with chirp-coded excitation modulated by a Tukey window can acquire accurate, high-quality elastography images.
format Online
Article
Text
id pubmed-5458841
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-54588412017-07-28 Ultrasound Elasticity Imaging System with Chirp-Coded Excitation for Assessing Biomechanical Properties of Elasticity Phantom Chun, Guan-Chun Chiang, Hsing-Jung Lin, Kuan-Hung Li, Chien-Ming Chen, Pei-Jarn Chen, Tainsong Materials (Basel) Article The biomechanical properties of soft tissues vary with pathological phenomenon. Ultrasound elasticity imaging is a noninvasive method used to analyze the local biomechanical properties of soft tissues in clinical diagnosis. However, the echo signal-to-noise ratio (eSNR) is diminished because of the attenuation of ultrasonic energy by soft tissues. Therefore, to improve the quality of elastography, the eSNR and depth of ultrasound penetration must be increased using chirp-coded excitation. Moreover, the low axial resolution of ultrasound images generated by a chirp-coded pulse must be increased using an appropriate compression filter. The main aim of this study is to develop an ultrasound elasticity imaging system with chirp-coded excitation using a Tukey window for assessing the biomechanical properties of soft tissues. In this study, we propose an ultrasound elasticity imaging system equipped with a 7.5-MHz single-element transducer and polymethylpentene compression plate to measure strains in soft tissues. Soft tissue strains were analyzed using cross correlation (CC) and absolution difference (AD) algorithms. The optimal parameters of CC and AD algorithms used for the ultrasound elasticity imaging system with chirp-coded excitation were determined by measuring the elastographic signal-to-noise ratio (SNRe) of a homogeneous phantom. Moreover, chirp-coded excitation and short pulse excitation were used to measure the elasticity properties of the phantom. The elastographic qualities of the tissue-mimicking phantom were assessed in terms of Young’s modulus and elastographic contrast-to-noise ratio (CNRe). The results show that the developed ultrasound elasticity imaging system with chirp-coded excitation modulated by a Tukey window can acquire accurate, high-quality elastography images. MDPI 2015-12-03 /pmc/articles/PMC5458841/ /pubmed/28793718 http://dx.doi.org/10.3390/ma8125458 Text en © 2015 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Chun, Guan-Chun
Chiang, Hsing-Jung
Lin, Kuan-Hung
Li, Chien-Ming
Chen, Pei-Jarn
Chen, Tainsong
Ultrasound Elasticity Imaging System with Chirp-Coded Excitation for Assessing Biomechanical Properties of Elasticity Phantom
title Ultrasound Elasticity Imaging System with Chirp-Coded Excitation for Assessing Biomechanical Properties of Elasticity Phantom
title_full Ultrasound Elasticity Imaging System with Chirp-Coded Excitation for Assessing Biomechanical Properties of Elasticity Phantom
title_fullStr Ultrasound Elasticity Imaging System with Chirp-Coded Excitation for Assessing Biomechanical Properties of Elasticity Phantom
title_full_unstemmed Ultrasound Elasticity Imaging System with Chirp-Coded Excitation for Assessing Biomechanical Properties of Elasticity Phantom
title_short Ultrasound Elasticity Imaging System with Chirp-Coded Excitation for Assessing Biomechanical Properties of Elasticity Phantom
title_sort ultrasound elasticity imaging system with chirp-coded excitation for assessing biomechanical properties of elasticity phantom
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458841/
https://www.ncbi.nlm.nih.gov/pubmed/28793718
http://dx.doi.org/10.3390/ma8125458
work_keys_str_mv AT chunguanchun ultrasoundelasticityimagingsystemwithchirpcodedexcitationforassessingbiomechanicalpropertiesofelasticityphantom
AT chianghsingjung ultrasoundelasticityimagingsystemwithchirpcodedexcitationforassessingbiomechanicalpropertiesofelasticityphantom
AT linkuanhung ultrasoundelasticityimagingsystemwithchirpcodedexcitationforassessingbiomechanicalpropertiesofelasticityphantom
AT lichienming ultrasoundelasticityimagingsystemwithchirpcodedexcitationforassessingbiomechanicalpropertiesofelasticityphantom
AT chenpeijarn ultrasoundelasticityimagingsystemwithchirpcodedexcitationforassessingbiomechanicalpropertiesofelasticityphantom
AT chentainsong ultrasoundelasticityimagingsystemwithchirpcodedexcitationforassessingbiomechanicalpropertiesofelasticityphantom