Cargando…

All atom NMDA receptor transmembrane domain model development and simulations in lipid bilayers and water

N-methyl-d-aspartate receptors (NMDARs) are members of the ionotropic glutamate receptor family that mediate excitatory synaptic transmission in the central nervous system. The channels of NMDARs are permeable to Ca(2+) but blocked by Mg(2+), distinctive properties that underlie essential brain proc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mesbahi-Vasey, Samaneh, Veras, Lea, Yonkunas, Michael, Johnson, Jon W., Kurnikova, Maria G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459333/ https://www.ncbi.nlm.nih.gov/pubmed/28582391 http://dx.doi.org/10.1371/journal.pone.0177686

Ejemplares similares

Inhibition of NMDA receptors through a membrane-to-channel path
por: Wilcox, Madeleine R., et al.
Publicado: (2022)

Role of the Ion Channel Extracellular Collar in AMPA Receptor Gating
por: Yelshanskaya, Maria V., et al.
Publicado: (2017)

All-Atom Molecular Dynamics Elucidating Molecular Mechanisms of Single-Transmembrane Model Peptide Dimerization in a Lipid Bilayer
por: Itaya, Hayato, et al.
Publicado: (2021)

Chaperoning transmembrane helices in the lipid bilayer
por: Zhang, Qi, et al.
Publicado: (2020)

The Hydrophobic Effect Contributes to the Closed State of a Simplified Ion Channel through a Conserved Hydrophobic Patch at the Pore-Helix Crossing
por: Yonkunas, Michael, et al.
Publicado: (2015)

A Helix Heterodimer in a Lipid Bilayer: Prediction of the Structure of an Integrin Transmembrane Domain via Multiscale Simulations
por: Kalli, Antreas C., et al.
Publicado: (2011)

Role of Transmembrane Proteins for Phase Separation and Domain Registration in Asymmetric Lipid Bilayers
por: Bossa, Guilherme Volpe, et al.
Publicado: (2019)

Crosslinking Constraints and Computational Models as Complementary Tools in Modeling the Extracellular Domain of the Glycine Receptor
por: Liu, Zhenyu, et al.
Publicado: (2014)

An investigation of the effect of membrane curvature on transmembrane-domain dependent protein sorting in lipid bilayers
por: Fossati, Matteo, et al.
Publicado: (2014)

Lipid Bilayer Composition Affects Transmembrane Protein Orientation and Function
por: Hickey, Katie D., et al.
Publicado: (2011)

Structure and drug binding of the SARS-CoV-2 envelope protein transmembrane domain in lipid bilayers
por: Mandala, Venkata S., et al.
Publicado: (2020)

The Interaction of the Transmembrane Domain of SARS-CoV-2 E-Protein with Glycyrrhizic Acid in Lipid Bilayer
por: Kononova, Polina A., et al.
Publicado: (2023)

All-atom simulations and free-energy calculations of coiled-coil peptides with lipid bilayers: binding strength, structural transition, and effect on lipid dynamics
por: Woo, Sun Young, et al.
Publicado: (2016)

All-atom molecular dynamics simulations of Synaptotagmin-SNARE-complexin complexes bridging a vesicle and a flat lipid bilayer
por: Rizo, Josep, et al.
Publicado: (2022)

A Portable Lipid Bilayer System for Environmental Sensing with a Transmembrane Protein
por: Kawano, Ryuji, et al.
Publicado: (2014)

Proton-Based Structural Analysis of a Heptahelical Transmembrane Protein in Lipid Bilayers
por: Lalli, Daniela, et al.
Publicado: (2017)

The Transmembrane Conformation of the Influenza B Virus M2 Protein in Lipid Bilayers
por: Mandala, Venkata S., et al.
Publicado: (2019)

Water Pores in Planar Lipid Bilayers at Fast and Slow Rise of Transmembrane Voltage
por: Maček Lebar, Alenka, et al.
Publicado: (2021)

β-Glutamine-mediated self-association of transmembrane β-peptides within lipid bilayers
por: Rost, U., et al.
Publicado: (2016)

TMPL: a database of experimental and theoretical transmembrane protein models positioned in the lipid bilayer
por: Postic, Guillaume, et al.
Publicado: (2017)

An AFM study of solid-phase bilayers of unsaturated PC lipids and the lateral distribution of the transmembrane model peptide WALP23 in these bilayers
por: Yarrow, F.
Publicado: (2011)

All-Atom Structural Models of the Transmembrane Domains of Insulin and Type 1 Insulin-Like Growth Factor Receptors
por: Mohammadiarani, Hossein, et al.
Publicado: (2016)

Impact of Bilayer Lipid Composition on the Structure and Topology of the Transmembrane Amyloid Precursor C99 Protein
por: Song, Yuanli, et al.
Publicado: (2014)

Domain Localization by Graphene Oxide in Supported Lipid Bilayers
por: Tero, Ryugo, et al.
Publicado: (2023)

Residual Interactions of LL-37 with POPC and POPE:POPG Bilayer Model Studied by All-Atom Molecular Dynamics Simulation
por: Yusuf, Muhammad, et al.
Publicado: (2022)

Conformational and lipid bilayer-perturbing properties of Marburg virus GP2 segments containing the fusion loop and membrane-proximal external region/transmembrane domain
por: Liu, Nina, et al.
Publicado: (2019)

Modulation of Photoinduced Transmembrane Currents in a Fullerene-Doped Freestanding Lipid Bilayer by a Lateral Bias
por: Ma, Teng, et al.
Publicado: (2019)

Parallel Recordings of Transmembrane hERG Channel Currents Based on Solvent-Free Lipid Bilayer Microarray
por: Miyata, Ryusuke, et al.
Publicado: (2021)

Preparation of DOPC and DPPC Supported Planar Lipid Bilayers for Atomic Force Microscopy and Atomic Force Spectroscopy
por: Attwood, Simon J., et al.
Publicado: (2013)

Formation of Cell Membrane Component Domains in Artificial Lipid Bilayer
por: Tero, Ryugo, et al.
Publicado: (2017)

Effect of CM15 on Supported Lipid Bilayer Probed by Atomic Force Microscopy
por: Walsh, Olivia D., et al.
Publicado: (2023)

How Does a Voltage Sensor Interact with a Lipid Bilayer? Simulations of a Potassium Channel Domain
por: Sands, Zara A., et al.
Publicado: (2007)

Localized Lipid Packing of Transmembrane Domains Impedes Integrin Clustering
por: Mehrbod, Mehrdad, et al.
Publicado: (2013)

Role of the Lipid Environment in the Dimerization of Transmembrane Domains of Glycophorin A
por: Kuznetsov, A. S., et al.
Publicado: (2015)

Divergent roles of a peripheral transmembrane segment in AMPA and NMDA receptors
por: Amin, Johansen B., et al.
Publicado: (2017)

Interactions of the EGFR juxtamembrane domain with PIP(2)-containing lipid bilayers: Insights from multiscale molecular dynamics simulations()
por: Abd Halim, Khairul Bariyyah, et al.
Publicado: (2015)

Supramolecular chemistry in lipid bilayer membranes
por: Bickerton, Laura E., et al.
Publicado: (2021)

Lipid Clustering Correlates with Membrane Curvature as Revealed by Molecular Simulations of Complex Lipid Bilayers
por: Koldsø, Heidi, et al.
Publicado: (2014)

Dimeric Structure of the Transmembrane Domain of Glycophorin A in Lipidic and Detergent Environments
por: Mineev, K.S., et al.
Publicado: (2011)

t-SNARE Transmembrane Domain Clustering Modulates Lipid Organization and Membrane Curvature
por: Sharma, Satyan, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_sdacbv7mlcv02n61s23caea3p9