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Catechin and epicatechin reduce mitochondrial dysfunction and oxidative stress induced by amiodarone in human lung fibroblasts

BACKGROUND: Amiodarone (AMD) and its metabolite N-desethylamiodarone can cause some adverse effects, which include pulmonary toxicity. Some studies suggest that mitochondrial dysfunction and oxidative stress may play a role in these adverse effects. Catechin and epicatechin are recognized as importa...

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Detalles Bibliográficos
Autores principales:	Silva Santos, Luciana Fernandes, Stolfo, Adriana, Calloni, Caroline, Salvador, Mirian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459414/ https://www.ncbi.nlm.nih.gov/pubmed/28607618 http://dx.doi.org/10.1016/j.joa.2016.09.004

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