SUMO regulates p21(Cip1) intracellular distribution and with p21(Cip1) facilitates multiprotein complex formation in the nucleolus upon DNA damage

We previously showed that p21(Cip1) transits through the nucleolus on its way from the nucleus to the cytoplasm and that DNA damage inhibits this transit and induces the formation of p21(Cip1)-containing intranucleolar bodies (INoBs). Here, we demonstrate that these INoBs also contain SUMO-1 and UBC...

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Detalles Bibliográficos
Autores principales: Brun, Sonia, Abella, Neus, Berciano, Maria T., Tapia, Olga, Jaumot, Montserrat, Freire, Raimundo, Lafarga, Miguel, Agell, Neus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459497/
https://www.ncbi.nlm.nih.gov/pubmed/28582471
http://dx.doi.org/10.1371/journal.pone.0178925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459497/
https://www.ncbi.nlm.nih.gov/pubmed/28582471
http://dx.doi.org/10.1371/journal.pone.0178925

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