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SUMO regulates p21(Cip1) intracellular distribution and with p21(Cip1) facilitates multiprotein complex formation in the nucleolus upon DNA damage
We previously showed that p21(Cip1) transits through the nucleolus on its way from the nucleus to the cytoplasm and that DNA damage inhibits this transit and induces the formation of p21(Cip1)-containing intranucleolar bodies (INoBs). Here, we demonstrate that these INoBs also contain SUMO-1 and UBC...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459497/ https://www.ncbi.nlm.nih.gov/pubmed/28582471 http://dx.doi.org/10.1371/journal.pone.0178925 |