Mechanistic Modelling of Drug-Induced Liver Injury: Investigating the Role of Innate Immune Responses

Drug-induced liver injury (DILI) remains an adverse event of significant concern for drug development and marketed drugs, and the field would benefit from better tools to identify liver liabilities early in development and/or to mitigate potential DILI risk in otherwise promising drugs. DILIsym soft...

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Detalles Bibliográficos
Autores principales: Shoda, Lisl KM, Battista, Christina, Siler, Scott Q, Pisetsky, David S, Watkins, Paul B, Howell, Brett A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459514/
https://www.ncbi.nlm.nih.gov/pubmed/28615926
http://dx.doi.org/10.1177/1177625017696074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459514/
https://www.ncbi.nlm.nih.gov/pubmed/28615926
http://dx.doi.org/10.1177/1177625017696074

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