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Structural basis of cooperativity in kinesin revealed by 3D reconstruction of a two-head-bound state on microtubules
The detailed basis of walking by dimeric molecules of kinesin along microtubules has remained unclear, partly because available structural methods have been unable to capture microtubule-bound intermediates of this process. Utilizing novel electron cryomicroscopy methods, we solved structures of mic...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459574/ https://www.ncbi.nlm.nih.gov/pubmed/28504639 http://dx.doi.org/10.7554/eLife.24490 |