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Pausing guides RNA folding to populate transiently stable RNA structures for riboswitch-based transcription regulation

In bacteria, the regulation of gene expression by cis-acting transcriptional riboswitches located in the 5'-untranslated regions of messenger RNA requires the temporal synchronization of RNA synthesis and ligand binding-dependent conformational refolding. Ligand binding to the aptamer domain of...

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Detalles Bibliográficos
Autores principales: Steinert, Hannah, Sochor, Florian, Wacker, Anna, Buck, Janina, Helmling, Christina, Hiller, Fabian, Keyhani, Sara, Noeske, Jonas, Grimm, Steffen, Rudolph, Martin M, Keller, Heiko, Mooney, Rachel Anne, Landick, Robert, Suess, Beatrix, Fürtig, Boris, Wöhnert, Jens, Schwalbe, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459577/
https://www.ncbi.nlm.nih.gov/pubmed/28541183
http://dx.doi.org/10.7554/eLife.21297