IgG-specific cell-based assay detects potentially pathogenic MuSK-Abs in seronegative MG

OBJECTIVE: To increase the detection of MuSK-Abs using a CBA and test their pathogenicity. METHODS: Sera from 69 MuSK-RIA–positive patients with myasthenia gravis (MG) (Definite MuSK-MG), 169 patients negative for MuSK-RIA and AChR-RIA (seronegative MG, SNMG), 35 healthy individuals (healthy control...

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Detalles Bibliográficos
Autores principales: Huda, Saif, Waters, Patrick, Woodhall, Mark, Leite, Maria Isabel, Jacobson, Leslie, De Rosa, Anna, Maestri, Michelangelo, Ricciardi, Roberta, Heckmann, Jeannine M., Maniaol, Angelina, Evoli, Amelia, Cossins, Judy, Hilton-Jones, David, Vincent, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459793/
https://www.ncbi.nlm.nih.gov/pubmed/28626780
http://dx.doi.org/10.1212/NXI.0000000000000357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459793/
https://www.ncbi.nlm.nih.gov/pubmed/28626780
http://dx.doi.org/10.1212/NXI.0000000000000357

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