LRRK2 levels in immune cells are increased in Parkinson’s disease

Mutations associated with leucine-rich repeat kinase 2 are the most common known cause of Parkinson’s disease. The known expression of leucine-rich repeat kinase 2 in immune cells and its negative regulatory function of nuclear factor of activated T cells implicates leucine-rich repeat kinase 2 in t...

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Detalles Bibliográficos
Autores principales: Cook, D. A., Kannarkat, G. T., Cintron, A. F., Butkovich, Laura M., Fraser, Kyle B., Chang, J., Grigoryan, N., Factor, S. A., West, Andrew B., Boss, J. M., Tansey, M. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459798/
https://www.ncbi.nlm.nih.gov/pubmed/28649611
http://dx.doi.org/10.1038/s41531-017-0010-8

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