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Normalization of adiponectin concentrations by leptin replacement in ob/ob mice is accompanied by reductions in systemic oxidative stress and inflammation
The circulating concentrations of adiponectin, an antidiabetic adipokine, have been shown to be reduced in obesity, in relation to an increase in inflammation. The aim of the present work was to assess the effect of leptin replacement on adiponectin levels and expression as well as on markers of oxi...
Autores principales: | Frühbeck, Gema, Catalán, Victoria, Rodríguez, Amaia, Ramírez, Beatriz, Becerril, Sara, Portincasa, Piero, Gómez-Ambrosi, Javier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459809/ https://www.ncbi.nlm.nih.gov/pubmed/28584304 http://dx.doi.org/10.1038/s41598-017-02848-0 |
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