Whole Blood Profiling of Bacillus Calmette–Guérin-Induced Trained Innate Immunity in Infants Identifies Epidermal Growth Factor, IL-6, Platelet-Derived Growth Factor-AB/BB, and Natural Killer Cell Activation

Vaccination of infants with bacillus Calmette–Guérin (BCG) activates both the innate and adaptive arms of the immune response. The antimycobacterial effects of these responses most likely account for the ability of BCG to protect against childhood forms of tuberculosis (TB). There is also evidence f...

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Detalles Bibliográficos
Autores principales: Smith, Steven G., Kleinnijenhuis, Johanneke, Netea, Mihai G., Dockrell, Hazel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459878/
https://www.ncbi.nlm.nih.gov/pubmed/28634479
http://dx.doi.org/10.3389/fimmu.2017.00644

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