Redesigning metabolism based on orthogonality principles

Modifications made during metabolic engineering for overproduction of chemicals have network-wide effects on cellular function due to ubiquitous metabolic interactions. These interactions, that make metabolic network structures robust and optimized for cell growth, act to constrain the capability of...

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Detalles Bibliográficos
Autores principales: Pandit, Aditya Vikram, Srinivasan, Shyam, Mahadevan, Radhakrishnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459945/
https://www.ncbi.nlm.nih.gov/pubmed/28555623
http://dx.doi.org/10.1038/ncomms15188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459945/
https://www.ncbi.nlm.nih.gov/pubmed/28555623
http://dx.doi.org/10.1038/ncomms15188

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