Drug-seeking motivation level in male rats determines offspring susceptibility or resistance to cocaine-seeking behaviour

Liability to develop drug addiction is heritable, but the precise contribution of non-Mendelian factors is not well understood. Here we separate male rats into addiction-like and non-addiction-like groups, based on their incentive motivation to seek cocaine. We find that the high incentive respondin...

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Detalles Bibliográficos
Autores principales: Le, Qiumin, Yan, Biao, Yu, Xiangchen, Li, Yanqing, Song, Haikun, Zhu, Huiwen, Hou, Weiqing, Ma, Dingailu, Wu, Feizhen, Zhou, Yuqing, Ma, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459992/
https://www.ncbi.nlm.nih.gov/pubmed/28556835
http://dx.doi.org/10.1038/ncomms15527

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