Clonally stable Vκ allelic choice instructs Igκ repertoire

Although much has been done to understand how rearrangement of the Igκ locus is regulated during B-cell development, little is known about the way the variable (V) segments themselves are selected. Here we show, using B6/Cast hybrid pre-B-cell clones, that a limited number of V segments on each alle...

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Detalles Bibliográficos
Autores principales: Levin-Klein, Rena, Fraenkel, Shira, Lichtenstein, Michal, Matheson, Louise S., Bartok, Osnat, Nevo, Yuval, Kadener, Sebastian, Corcoran, Anne E., Cedar, Howard, Bergman, Yehudit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459994/
https://www.ncbi.nlm.nih.gov/pubmed/28555639
http://dx.doi.org/10.1038/ncomms15575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459994/
https://www.ncbi.nlm.nih.gov/pubmed/28555639
http://dx.doi.org/10.1038/ncomms15575

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