CRISPR/Cas9 targeting events cause complex deletions and insertions at 17 sites in the mouse genome

Although CRISPR/Cas9 genome editing has provided numerous opportunities to interrogate the functional significance of any given genomic site, there is a paucity of data on the extent of molecular scars inflicted on the mouse genome. Here we interrogate the molecular consequences of CRISPR/Cas9-media...

Descripción completa

Detalles Bibliográficos
Autores principales: Shin, Ha Youn, Wang, Chaochen, Lee, Hye Kyung, Yoo, Kyung Hyun, Zeng, Xianke, Kuhns, Tyler, Yang, Chul Min, Mohr, Teresa, Liu, Chengyu, Hennighausen, Lothar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460021/
https://www.ncbi.nlm.nih.gov/pubmed/28561021
http://dx.doi.org/10.1038/ncomms15464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460021/
https://www.ncbi.nlm.nih.gov/pubmed/28561021
http://dx.doi.org/10.1038/ncomms15464

Ejemplares similares