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CRISPR/Cas9 targeting events cause complex deletions and insertions at 17 sites in the mouse genome
Although CRISPR/Cas9 genome editing has provided numerous opportunities to interrogate the functional significance of any given genomic site, there is a paucity of data on the extent of molecular scars inflicted on the mouse genome. Here we interrogate the molecular consequences of CRISPR/Cas9-media...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460021/ https://www.ncbi.nlm.nih.gov/pubmed/28561021 http://dx.doi.org/10.1038/ncomms15464 |