GCH1 plays a role in the high-altitude adaptation of Tibetans

Tibetans are well adapted to high-altitude hypoxia. Previous genome-wide scans have reported many candidate genes for this adaptation, but only a few have been studied. Here we report on a hypoxia gene (GCH1, GTP-cyclohydrolase I), involved in maintaining nitric oxide synthetase (NOS) function and n...

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Detalles Bibliográficos
Autores principales: Guo, Yong-Bo, He, Yao-Xi, Cui, Chao-Ying, Ou, zhuluobu, Bai, makangzhuo, Duo, jizhuoma, De, jiquzong, Bian, ba, Yi, Peng, Bai, Cai-juan, Gong, galanzi, Pan, Yong-Yue, la Qu, Kang, min, Ciren, yangji, Bai, mayangji, Guo, Wei, la Yang, Zhang, Hui, Zhang, Xiao-Ming, Zheng, Wang-Shan, Xu, Shu-Hua, Chen, Hua, Zhao, Sheng-Guo, Cai, Yuan, Liu, Shi-Ming, Tian-Yi, Wu, Qi, Xue-Bin, Su, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460084/
https://www.ncbi.nlm.nih.gov/pubmed/28585439
http://dx.doi.org/10.24272/j.issn.2095-8137.2017.037

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