Characterization of developmental defects in the forebrain resulting from hyperactivated mTOR signaling by integrative analysis of transcriptomic and proteomic data

Hyperactivated mTOR signaling in the developing brain has been implicated in multiple forms of pathology including tuberous sclerosis complex (TSC). To date, various phenotypic defects such as cortical lamination irregularity, subependymal nodule formation, dysmorphic astrocyte differentiation and d...

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Detalles Bibliográficos
Autores principales: Shin, Jiheon, Kim, Minhyung, Jung, Hee-Jung, Cha, Hye Lim, Suh-Kim, Haeyoung, Ahn, Sanghyun, Jung, Jaehoon, Kim, YounAh, Jun, Yukyung, Lee, Sanghyuk, Hwang, Daehee, Kim, Jaesang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460284/
https://www.ncbi.nlm.nih.gov/pubmed/28588230
http://dx.doi.org/10.1038/s41598-017-02842-6

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