Regio- and Stereoselective Radical Perfluoroalkyltriflation of Alkynes Using Phenyl(perfluoroalkyl)iodonium Triflates

[Image: see text] A method for regio- and stereoselective anti-addition of the perfluoroalkyl and the triflate group of phenyl(perfluoroalkyl)iodonium triflates to alkynes is presented. The radical reaction uses cheap CuCl as a smart initiator and can be conducted in gram scale. The perfluoroalkyltr...

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Autores principales: Wang, Xi, Studer, Armido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460293/
https://www.ncbi.nlm.nih.gov/pubmed/28517935
http://dx.doi.org/10.1021/acs.orglett.7b01215
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author Wang, Xi
Studer, Armido
author_facet Wang, Xi
Studer, Armido
author_sort Wang, Xi
collection PubMed
description [Image: see text] A method for regio- and stereoselective anti-addition of the perfluoroalkyl and the triflate group of phenyl(perfluoroalkyl)iodonium triflates to alkynes is presented. The radical reaction uses cheap CuCl as a smart initiator and can be conducted in gram scale. The perfluoroalkyltriflated products are readily further functionalized, rendering this transformation valuable.
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spelling pubmed-54602932017-06-08 Regio- and Stereoselective Radical Perfluoroalkyltriflation of Alkynes Using Phenyl(perfluoroalkyl)iodonium Triflates Wang, Xi Studer, Armido Org Lett [Image: see text] A method for regio- and stereoselective anti-addition of the perfluoroalkyl and the triflate group of phenyl(perfluoroalkyl)iodonium triflates to alkynes is presented. The radical reaction uses cheap CuCl as a smart initiator and can be conducted in gram scale. The perfluoroalkyltriflated products are readily further functionalized, rendering this transformation valuable. American Chemical Society 2017-05-18 2017-06-02 /pmc/articles/PMC5460293/ /pubmed/28517935 http://dx.doi.org/10.1021/acs.orglett.7b01215 Text en Copyright © 2017 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Wang, Xi
Studer, Armido
Regio- and Stereoselective Radical Perfluoroalkyltriflation of Alkynes Using Phenyl(perfluoroalkyl)iodonium Triflates
title Regio- and Stereoselective Radical Perfluoroalkyltriflation of Alkynes Using Phenyl(perfluoroalkyl)iodonium Triflates
title_full Regio- and Stereoselective Radical Perfluoroalkyltriflation of Alkynes Using Phenyl(perfluoroalkyl)iodonium Triflates
title_fullStr Regio- and Stereoselective Radical Perfluoroalkyltriflation of Alkynes Using Phenyl(perfluoroalkyl)iodonium Triflates
title_full_unstemmed Regio- and Stereoselective Radical Perfluoroalkyltriflation of Alkynes Using Phenyl(perfluoroalkyl)iodonium Triflates
title_short Regio- and Stereoselective Radical Perfluoroalkyltriflation of Alkynes Using Phenyl(perfluoroalkyl)iodonium Triflates
title_sort regio- and stereoselective radical perfluoroalkyltriflation of alkynes using phenyl(perfluoroalkyl)iodonium triflates
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460293/
https://www.ncbi.nlm.nih.gov/pubmed/28517935
http://dx.doi.org/10.1021/acs.orglett.7b01215
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AT studerarmido regioandstereoselectiveradicalperfluoroalkyltriflationofalkynesusingphenylperfluoroalkyliodoniumtriflates

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