Acetic Acid Promoted Redox Annulations with Dual C–H Functionalization

[Image: see text] Amines such as 1,2,3,4-tetrahydroisoquinoline undergo redox-neutral annulations with 2-alkylquinoline-3-carbaldehydes as well as the corresponding 4-alkyl isomers and pyridine analogues. These processes involve dual C–H bond functionalization. Acetic acid is used as a cosolvent and...

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Detalles Bibliográficos
Autores principales: Zhu, Zhengbo, Seidel, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460294/
https://www.ncbi.nlm.nih.gov/pubmed/28510444
http://dx.doi.org/10.1021/acs.orglett.7b01047
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author Zhu, Zhengbo
Seidel, Daniel
author_facet Zhu, Zhengbo
Seidel, Daniel
author_sort Zhu, Zhengbo
collection PubMed
description [Image: see text] Amines such as 1,2,3,4-tetrahydroisoquinoline undergo redox-neutral annulations with 2-alkylquinoline-3-carbaldehydes as well as the corresponding 4-alkyl isomers and pyridine analogues. These processes involve dual C–H bond functionalization. Acetic acid is used as a cosolvent and acts as the sole promoter of these transformations.
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spelling pubmed-54602942017-06-08 Acetic Acid Promoted Redox Annulations with Dual C–H Functionalization Zhu, Zhengbo Seidel, Daniel Org Lett [Image: see text] Amines such as 1,2,3,4-tetrahydroisoquinoline undergo redox-neutral annulations with 2-alkylquinoline-3-carbaldehydes as well as the corresponding 4-alkyl isomers and pyridine analogues. These processes involve dual C–H bond functionalization. Acetic acid is used as a cosolvent and acts as the sole promoter of these transformations. American Chemical Society 2017-05-16 2017-06-02 /pmc/articles/PMC5460294/ /pubmed/28510444 http://dx.doi.org/10.1021/acs.orglett.7b01047 Text en Copyright © 2017 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Zhu, Zhengbo
Seidel, Daniel
Acetic Acid Promoted Redox Annulations with Dual C–H Functionalization
title Acetic Acid Promoted Redox Annulations with Dual C–H Functionalization
title_full Acetic Acid Promoted Redox Annulations with Dual C–H Functionalization
title_fullStr Acetic Acid Promoted Redox Annulations with Dual C–H Functionalization
title_full_unstemmed Acetic Acid Promoted Redox Annulations with Dual C–H Functionalization
title_short Acetic Acid Promoted Redox Annulations with Dual C–H Functionalization
title_sort acetic acid promoted redox annulations with dual c–h functionalization
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460294/
https://www.ncbi.nlm.nih.gov/pubmed/28510444
http://dx.doi.org/10.1021/acs.orglett.7b01047
work_keys_str_mv AT zhuzhengbo aceticacidpromotedredoxannulationswithdualchfunctionalization
AT seideldaniel aceticacidpromotedredoxannulationswithdualchfunctionalization

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