Nuclear Protein in Testis Midline Carcinoma Presenting in an Infant as a Pericardial Mass with Staging by (18)F-Fluorodeoxyglucose-positron Emission Tomography/Computed Tomography

Nuclear protein in testis (NUT) midline carcinoma (NMC) is a rare, aggressive, lethal, epithelioid, poorly differentiated cancer first described in Japan in 1991, unique in that is defined genetically rather than by histological tissue of origin. It usually arises in the body midline and presents as...

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Autores principales: Perkins, Crystal, Pucar, Darko, McDonough, Colleen H., Williams, Hadyn T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460312/
https://www.ncbi.nlm.nih.gov/pubmed/28670187
http://dx.doi.org/10.4103/1450-1147.207284
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author Perkins, Crystal
Pucar, Darko
McDonough, Colleen H.
Williams, Hadyn T.
author_facet Perkins, Crystal
Pucar, Darko
McDonough, Colleen H.
Williams, Hadyn T.
author_sort Perkins, Crystal
collection PubMed
description Nuclear protein in testis (NUT) midline carcinoma (NMC) is a rare, aggressive, lethal, epithelioid, poorly differentiated cancer first described in Japan in 1991, unique in that is defined genetically rather than by histological tissue of origin. It usually arises in the body midline and presents as a mass with metastasis. An infant presenting with pneumonia was found to have a pericardial mass, NMC resected, and subsequent staging positron emission tomography (PET) showing residual mediastinal tumor and midline abdominal metastases. Fewer than 100 cases of NMC have been reported in the literature, and PET appears to be the imaging modality of choice in complete staging and evaluation of treatment response.
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spelling pubmed-54603122017-07-01 Nuclear Protein in Testis Midline Carcinoma Presenting in an Infant as a Pericardial Mass with Staging by (18)F-Fluorodeoxyglucose-positron Emission Tomography/Computed Tomography Perkins, Crystal Pucar, Darko McDonough, Colleen H. Williams, Hadyn T. World J Nucl Med Case Report Nuclear protein in testis (NUT) midline carcinoma (NMC) is a rare, aggressive, lethal, epithelioid, poorly differentiated cancer first described in Japan in 1991, unique in that is defined genetically rather than by histological tissue of origin. It usually arises in the body midline and presents as a mass with metastasis. An infant presenting with pneumonia was found to have a pericardial mass, NMC resected, and subsequent staging positron emission tomography (PET) showing residual mediastinal tumor and midline abdominal metastases. Fewer than 100 cases of NMC have been reported in the literature, and PET appears to be the imaging modality of choice in complete staging and evaluation of treatment response. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5460312/ /pubmed/28670187 http://dx.doi.org/10.4103/1450-1147.207284 Text en Copyright: © 2017 World Journal of Nuclear Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Perkins, Crystal
Pucar, Darko
McDonough, Colleen H.
Williams, Hadyn T.
Nuclear Protein in Testis Midline Carcinoma Presenting in an Infant as a Pericardial Mass with Staging by (18)F-Fluorodeoxyglucose-positron Emission Tomography/Computed Tomography
title Nuclear Protein in Testis Midline Carcinoma Presenting in an Infant as a Pericardial Mass with Staging by (18)F-Fluorodeoxyglucose-positron Emission Tomography/Computed Tomography
title_full Nuclear Protein in Testis Midline Carcinoma Presenting in an Infant as a Pericardial Mass with Staging by (18)F-Fluorodeoxyglucose-positron Emission Tomography/Computed Tomography
title_fullStr Nuclear Protein in Testis Midline Carcinoma Presenting in an Infant as a Pericardial Mass with Staging by (18)F-Fluorodeoxyglucose-positron Emission Tomography/Computed Tomography
title_full_unstemmed Nuclear Protein in Testis Midline Carcinoma Presenting in an Infant as a Pericardial Mass with Staging by (18)F-Fluorodeoxyglucose-positron Emission Tomography/Computed Tomography
title_short Nuclear Protein in Testis Midline Carcinoma Presenting in an Infant as a Pericardial Mass with Staging by (18)F-Fluorodeoxyglucose-positron Emission Tomography/Computed Tomography
title_sort nuclear protein in testis midline carcinoma presenting in an infant as a pericardial mass with staging by (18)f-fluorodeoxyglucose-positron emission tomography/computed tomography
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460312/
https://www.ncbi.nlm.nih.gov/pubmed/28670187
http://dx.doi.org/10.4103/1450-1147.207284
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