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Single-cell study links metabolism with nutrient signaling and reveals sources of variability

BACKGROUND: The yeast AMPK/SNF1 pathway is best known for its role in glucose de/repression. When glucose becomes limited, the Snf1 kinase is activated and phosphorylates the transcriptional repressor Mig1, which is then exported from the nucleus. The exact mechanism how the Snf1-Mig1 pathway is reg...

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Detalles Bibliográficos
Autores principales:	Welkenhuysen, Niek, Borgqvist, Johannes, Backman, Mattias, Bendrioua, Loubna, Goksör, Mattias, Adiels, Caroline B, Cvijovic, Marija, Hohmann, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460408/ https://www.ncbi.nlm.nih.gov/pubmed/28583118 http://dx.doi.org/10.1186/s12918-017-0435-z

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