The structural assembly switch of cell division protein FtsZ probed with fluorescent allosteric inhibitors

FtsZ is a widely conserved tubulin-like GTPase that directs bacterial cell division and a new target for antibiotic discovery. This protein assembly machine cooperatively polymerizes forming single-stranded filaments, by means of self-switching between inactive and actively associating monomer confo...

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Detalles Bibliográficos
Autores principales: Artola, Marta, Ruíz-Avila, Laura B., Ramírez-Aportela, Erney, Martínez, R. Fernando, Araujo-Bazán, Lidia, Vázquez-Villa, Henar, Martín-Fontecha, Mar, Oliva, María A., Martín-Galiano, A. Javier, Chacón, Pablo, López-Rodríguez, María L., Andreu, José M., Huecas, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460597/
https://www.ncbi.nlm.nih.gov/pubmed/28616148
http://dx.doi.org/10.1039/c6sc03792e

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