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The Role of Epithelial to Mesenchymal Transition in Human Amniotic Membrane Rupture

CONTEXT: Biochemical weakening of the amnion is a major factor preceding preterm premature rupture of membranes (PPROMs), leading to preterm birth. Activation of matrix metalloproteinases (MMPs) is known to play a key role in collagen degradation of the amnion; however, epithelial to mesenchymal tra...

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Detalles Bibliográficos
Autores principales: Janzen, Carla, Sen, Suvajit, Lei, Margarida Y. Y., Gagliardi de Assumpcao, Marina, Challis, John, Chaudhuri, Gautam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460731/
https://www.ncbi.nlm.nih.gov/pubmed/28388726
http://dx.doi.org/10.1210/jc.2016-3150