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Intracellular zinc flux causes reactive oxygen species mediated mitochondrial dysfunction leading to cell death in Leishmania donovani
Leishmaniasis caused by Leishmania parasite is a global threat to public health and one of the most neglected tropical diseases. Therefore, the discovery of novel drug targets and effective drug is a major challenge and an important goal. Leishmania is an obligate intracellular parasite that alterna...
Autores principales: | Kumari, Anjali, Singh, Krishn Pratap, Mandal, Abhishek, Paswan, Ranjeet Kumar, Sinha, Preeti, Das, Pradeep, Ali, Vahab, Bimal, Sanjiva, Lal, Chandra Shekhar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460814/ https://www.ncbi.nlm.nih.gov/pubmed/28586364 http://dx.doi.org/10.1371/journal.pone.0178800 |
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