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Performance analysis of a new hypersonic vitrector system

PURPOSE: To evaluate porcine vitreous flow and water flow rates in a new prototype hypersonic vitrectomy system compared to currently available pneumatic guillotine vitrectors (GVs) systems. METHODS: Two vitrectors were tested, a prototype, ultrasound-powered, hypersonic vitrector (HV) and a GV. Por...

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Autores principales: Stanga, Paulo Eduardo, Pastor-Idoate, Salvador, Zambrano, Isaac, Carlin, Paul, McLeod, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460816/
https://www.ncbi.nlm.nih.gov/pubmed/28586375
http://dx.doi.org/10.1371/journal.pone.0178462
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author Stanga, Paulo Eduardo
Pastor-Idoate, Salvador
Zambrano, Isaac
Carlin, Paul
McLeod, David
author_facet Stanga, Paulo Eduardo
Pastor-Idoate, Salvador
Zambrano, Isaac
Carlin, Paul
McLeod, David
author_sort Stanga, Paulo Eduardo
collection PubMed
description PURPOSE: To evaluate porcine vitreous flow and water flow rates in a new prototype hypersonic vitrectomy system compared to currently available pneumatic guillotine vitrectors (GVs) systems. METHODS: Two vitrectors were tested, a prototype, ultrasound-powered, hypersonic vitrector (HV) and a GV. Porcine vitreous was obtained within 12 to 24 h of sacrifice and kept at 4°C. A vial of vitreous or water was placed on a precision balance and its weight measured before and after the use of each vitrector. Test parameters included changes in aspiration levels, vitrector gauge, cut rates for GVs, % ultrasound (US) power for HVs, and port size for HVs. Data was analysed using linear regression and t-tests. RESULTS: There was no difference in the total average mean water flow between the 25-gauge GV and the 25-gauge HV (t-test: P = 0.363); however, 25-gauge GV was superior (t-test: P < 0.001) in vitreous flow. The 23-gauge GV was only more efficient in water and vitreous removal than 23-gauge HV needle-1 (Port 0.0055) (t-test: P < 0.001). For HV, wall thickness and gauge had no effect on flow rates. Water and vitreous flows showed a direct correlation with increasing aspiration levels and % US power (p<0.05). CONCLUSIONS: The HV produced consistent water and vitreous flow rates across the range of US power and aspiration levels tested. Hypersonic vitrectomy may be a promising new alternative to the currently available guillotine-based technologies.
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spelling pubmed-54608162017-06-15 Performance analysis of a new hypersonic vitrector system Stanga, Paulo Eduardo Pastor-Idoate, Salvador Zambrano, Isaac Carlin, Paul McLeod, David PLoS One Research Article PURPOSE: To evaluate porcine vitreous flow and water flow rates in a new prototype hypersonic vitrectomy system compared to currently available pneumatic guillotine vitrectors (GVs) systems. METHODS: Two vitrectors were tested, a prototype, ultrasound-powered, hypersonic vitrector (HV) and a GV. Porcine vitreous was obtained within 12 to 24 h of sacrifice and kept at 4°C. A vial of vitreous or water was placed on a precision balance and its weight measured before and after the use of each vitrector. Test parameters included changes in aspiration levels, vitrector gauge, cut rates for GVs, % ultrasound (US) power for HVs, and port size for HVs. Data was analysed using linear regression and t-tests. RESULTS: There was no difference in the total average mean water flow between the 25-gauge GV and the 25-gauge HV (t-test: P = 0.363); however, 25-gauge GV was superior (t-test: P < 0.001) in vitreous flow. The 23-gauge GV was only more efficient in water and vitreous removal than 23-gauge HV needle-1 (Port 0.0055) (t-test: P < 0.001). For HV, wall thickness and gauge had no effect on flow rates. Water and vitreous flows showed a direct correlation with increasing aspiration levels and % US power (p<0.05). CONCLUSIONS: The HV produced consistent water and vitreous flow rates across the range of US power and aspiration levels tested. Hypersonic vitrectomy may be a promising new alternative to the currently available guillotine-based technologies. Public Library of Science 2017-06-06 /pmc/articles/PMC5460816/ /pubmed/28586375 http://dx.doi.org/10.1371/journal.pone.0178462 Text en © 2017 Stanga et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Stanga, Paulo Eduardo
Pastor-Idoate, Salvador
Zambrano, Isaac
Carlin, Paul
McLeod, David
Performance analysis of a new hypersonic vitrector system
title Performance analysis of a new hypersonic vitrector system
title_full Performance analysis of a new hypersonic vitrector system
title_fullStr Performance analysis of a new hypersonic vitrector system
title_full_unstemmed Performance analysis of a new hypersonic vitrector system
title_short Performance analysis of a new hypersonic vitrector system
title_sort performance analysis of a new hypersonic vitrector system
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460816/
https://www.ncbi.nlm.nih.gov/pubmed/28586375
http://dx.doi.org/10.1371/journal.pone.0178462
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