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Production of transgenic pig as an Alzheimer’s disease model using a multi-cistronic vector system

Alzheimer’s disease (AD) is a progressive neurodegenerative disease associated with memory loss and cognitive impairments. An AD transgenic (Tg) pig model would be useful for preclinical testing of therapeutic agents. We generated an AD Tg pig by somatic cell nuclear transfer (SCNT) using a multi-ci...

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Detalles Bibliográficos
Autores principales:	Lee, Seung-Eun, Hyun, Hyuk, Park, Mi-Ryung, Choi, Youngsok, Son, Yeo-Jin, Park, Yun-Gwi, Jeong, Sang-Gi, Shin, Min-Young, Ha, Hee-Jin, Hong, Hyun-Sok, Choi, Min-Keyung, Im, Gi-Sun, Park, Eung-Woo, Kim, Young-Ho, Park, Chankyu, Kim, Eun-Young, Park, Se-Pill
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460854/ https://www.ncbi.nlm.nih.gov/pubmed/28586343 http://dx.doi.org/10.1371/journal.pone.0177933

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