A prospective pilot study of genome-wide exome and transcriptome profiling in patients with small cell lung cancer progressing after first-line therapy

BACKGROUND: Small cell lung cancer (SCLC) that has progressed after first-line therapy is an aggressive disease with few effective therapeutic strategies. In this prospective study, we employed next-generation sequencing (NGS) to identify therapeutically actionable alterations to guide treatment for...

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Detalles Bibliográficos
Autores principales: Weiss, Glen J., Byron, Sara A., Aldrich, Jessica, Sangal, Ashish, Barilla, Heather, Kiefer, Jeffrey A., Carpten, John D., Craig, David W., Whitsett, Timothy G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460863/
https://www.ncbi.nlm.nih.gov/pubmed/28586388
http://dx.doi.org/10.1371/journal.pone.0179170

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