Cargando…
High Glucose Induces Mitochondrial Dysfunction in Retinal Müller Cells: Implications for Diabetic Retinopathy
PURPOSE: To investigate whether high glucose (HG) induces mitochondrial dysfunction and promotes apoptosis in retinal Müller cells. METHODS: Rat retinal Müller cells (rMC-1) grown in normal (N) or HG (30 mM glucose) medium for 7 days were subjected to MitoTracker Red staining to identify the mitocho...
Autores principales: | Tien, Thomas, Zhang, Joyce, Muto, Tetsuya, Kim, Dongjoon, Sarthy, Vijay P., Roy, Sayon |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460955/ https://www.ncbi.nlm.nih.gov/pubmed/28586916 http://dx.doi.org/10.1167/iovs.16-21355 |
Ejemplares similares
-
Effects of Diabetes on Mitochondrial Morphology and Its Implications in Diabetic Retinopathy
por: Kim, Dongjoon, et al.
Publicado: (2020) -
High Glucose Increases Binding of Lysyl Oxidase to Extracellular Matrix Proteins: Implications for Diabetic Retinopathy
por: Nguyen, Ngan-Ha, et al.
Publicado: (2020) -
High-Glucose-Induced Rab20 Upregulation Disrupts Gap Junction Intercellular Communication and Promotes Apoptosis in Retinal Endothelial and Müller Cells: Implications for Diabetic Retinopathy
por: Kim, Dongjoon, et al.
Publicado: (2020) -
Inhibition of Diabetes-Induced Lysyl Oxidase Overexpression Prevents Retinal Vascular Lesions Associated With Diabetic Retinopathy
por: Song, Brian, et al.
Publicado: (2018) -
Downregulation of Lysyl Oxidase Protects Retinal Endothelial Cells From High Glucose–Induced Apoptosis
por: Kim, Dongjoon, et al.
Publicado: (2017)