Cargando…

The Antitumor Effect of C-terminus of Hsp70-Interacting Protein via Degradation of c-Met in Small Cell Lung Cancer

BACKGROUND: The mesenchymal-epithelial transition factor (MET) receptor can be overexpressed in solid tumors, including small cell lung cancer (SCLC). However, the molecular mechanism regulating MET stability and turnover in SCLC remains undefined. One potential mechanism of MET regulation involves...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cho, Sung Ho, Kim, Jong In, Kim, Hyun Su, Park, Sung Dal, Jang, Kang Won
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society for Thoracic and Cardiovascular Surgery 2017
Materias:	Basic Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460961/ https://www.ncbi.nlm.nih.gov/pubmed/28593150 http://dx.doi.org/10.5090/kjtcs.2017.50.3.153

Ejemplares similares

C-terminus of Hsp70 Interacting Protein (CHIP) and Neurodegeneration: Lessons from the Bench and Bedside
por: Mylvaganam, Sivakami, et al.
Publicado: (2021)

Capsaicin binds the N-terminus of Hsp90, induces lysosomal degradation of Hsp70, and enhances the anti-tumor effects of 17-AAG (Tanespimycin)
por: Patwardhan, Chaitanya A., et al.
Publicado: (2023)

Identification of a Promiscuous Epitope Peptide Derived From HSP70
por: Matsui, Hiroto, et al.
Publicado: (2019)

C-terminus of HSC70-Interacting Protein (CHIP) Inhibits Adipocyte Differentiation via Ubiquitin- and Proteasome-Mediated Degradation of PPARγ
por: Kim, Jung-Hoon, et al.
Publicado: (2017)

Expression of carboxyl terminus of Hsp70-interacting protein (CHIP) indicates poor prognosis in human gallbladder carcinoma
por: LIANG, ZHE LONG, et al.
Publicado: (2013)

Prognostic Significance of p53, mTOR, c-Met, IGF-1R, and HSP70 Overexpression after the Resection of Hepatocellular Carcinoma
por: Kang, Gu Hyum, et al.
Publicado: (2014)

CLEC14a-HSP70-1A interaction regulates HSP70-1A-induced angiogenesis
por: Jang, Jihye, et al.
Publicado: (2017)

Ameliorating cancer cachexia by inhibiting cancer cell release of Hsp70 and Hsp90 with omeprazole
por: Liu, Zhelong, et al.
Publicado: (2021)

Novel c-Met inhibitor suppresses the growth of c-Met-addicted gastric cancer cells
por: Park, Chi Hoon, et al.
Publicado: (2016)

c-MET immunohistochemical expression in sporadic and inflammatory bowel disease associated lesions
por: Halliday, Grant, et al.
Publicado: (2022)

Protective Effects of Propolis Extract in a Rat Model of Traumatic Brain Injury via Hsp70 Induction
por: Tandean, Steven, et al.
Publicado: (2019)

Bacterial Hsp90 Facilitates the Degradation of Aggregation-Prone Hsp70–Hsp40 Substrates
por: Fauvet, Bruno, et al.
Publicado: (2021)

Crizotinib Exhibits Antitumor Activity by Targeting ALK Signaling not c-MET in Pancreatic Cancer
por: Yan, Hong Hua, et al.
Publicado: (2014)

ARD1-mediated Hsp70 acetylation balances stress-induced protein refolding and degradation
por: Seo, Ji Hae, et al.
Publicado: (2016)

Hsp70 and DNAJA2 limit CFTR levels through degradation
por: Kim Chiaw, Patrick, et al.
Publicado: (2019)

Prognostic impact of high c-Met expression in ovarian cancer: a meta-analysis
por: Kim, Jung Han, et al.
Publicado: (2018)

Carboxyl Terminus of Hsp70-Interacting Protein Is Increased in Serum and Cerebrospinal Fluid of Patients With Spinocerebellar Ataxia Type 3
por: Hu, Zheng-wei, et al.
Publicado: (2019)

Influence of L-arginine on expression of HSP70 and p-53 proteins – early biomarkers of cellular danger in renal tubular cells. Immunohistochemical assessment
por: Pedrycz, Agnieszka, et al.
Publicado: (2013)

Blockage of ETS homologous factor inhibits the proliferation and invasion of gastric cancer cells through the c-Met pathway
por: Gu, Meng-Li, et al.
Publicado: (2020)

Stoichiometric expression of mtHsp40 and mtHsp70 modulates mitochondrial morphology and cristae structure via Opa1(L) cleavage
por: Lee, Byoungchun, et al.
Publicado: (2015)

HSP70-1 is required for interleukin-5-induced angiogenic responses through eNOS pathway
por: Park, Sung Lyea, et al.
Publicado: (2017)

Selenocysteine modulates resistance to environmental stress and confers anti-aging effects in C. elegans
por: Kim, Jun-Sung, et al.
Publicado: (2017)

The Effects of Venlafaxine and Dexamethasone on the Expression of HSP70 in Rat C6 Glioma Cells
por: Yu, Jaehak, et al.
Publicado: (2010)

Protection against doxorubicin-induced myocardial dysfunction in mice by cardiac-specific expression of carboxyl terminus of hsp70-interacting protein
por: Wang, Lei, et al.
Publicado: (2016)

Activation of Hsp70 reduces neurotoxicity by promoting polyglutamine protein degradation
por: Wang, Adrienne M., et al.
Publicado: (2012)

Bat3 deficiency accelerates the degradation of Hsp70-2/HspA2 during spermatogenesis
por: Sasaki, Toru, et al.
Publicado: (2008)

Locked nucleic acid real-time polymerase chain reaction method identifying two polymorphisms of hepatitis B virus genotype C2 infections, rt269L and rt269I
por: Kim, Kijeong, et al.
Publicado: (2023)

HSP70 drives myoblast fusion during C2C12 myogenic differentiation
por: Thakur, Savant S., et al.
Publicado: (2020)

Patient-Derived Pancreatic Cancer Cells Induce C2C12 Myotube Atrophy by Releasing Hsp70 and Hsp90
por: Wu, Hong-Yu, et al.
Publicado: (2022)

Novel Peptide CM 7 Targeted c-Met with Antitumor Activity
por: Xia, Chunlei, et al.
Publicado: (2020)

HSP70 and ER expression in cervical intraepithelial neoplasia and cervical cancer.
por: Kim, K. K., et al.
Publicado: (1998)

Association Between c-Met and Lymphangiogenic Factors in Patients With Colorectal Cancer
por: Kim, Han Jo, et al.
Publicado: (2018)

Heat Shock Protein 70 (HSP70) Induction: Chaperonotherapy for Neuroprotection after Brain Injury
por: Kim, Jong Youl, et al.
Publicado: (2020)

Hsp70 gene association with nuclear speckles is Hsp70 promoter specific
por: Hu, Yan, et al.
Publicado: (2010)

Role of Ischemic Preconditioning in the Cardioprotective Mechanisms of Monomeric C-Reactive Protein-Deposited Myocardium in a Rat Model
por: Kim, Eun Na, et al.
Publicado: (2021)

An Intralysosomal hsp70 Is Required for a Selective Pathway of Lysosomal Protein Degradation
por: Agarraberes, Fernando A., et al.
Publicado: (1997)

Antitumor Activity of DFX117 by Dual Inhibition of c-Met and PI3Kα in Non-Small Cell Lung Cancer
por: Fan, Yanhua, et al.
Publicado: (2019)

Anti-leukemia activity of a Hsp70 inhibitor and its hybrid molecules
por: Park, Seong-Hyun, et al.
Publicado: (2017)

Synthetic Small Molecule Modulators of Hsp70 and Hsp40 Chaperones as Promising Anticancer Agents
por: Nitzsche, Bianca, et al.
Publicado: (2023)

Small GTPase Ran: Depicting the nucleotide-specific conformational landscape of the functionally important C-terminus
por: Czigleczki, Janka, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_09qnhhttqt6nf9l2597c98m6ig