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Interleukin 4 promotes the development of ex-Foxp3 Th2 cells during immunity to intestinal helminths

Immunity to intestinal helminth infections requires the rapid activation of T helper 2 cells (Th2 cells). However, simultaneous expansion of CD4(+)Foxp3(+) regulatory T cells (T reg cells) impedes protective responses, resulting in chronic infections. The ratio between T reg and effector T cells can...

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Detalles Bibliográficos
Autores principales:	Pelly, Victoria S., Coomes, Stephanie M., Kannan, Yashaswini, Gialitakis, Manolis, Entwistle, Lewis J., Perez-Lloret, Jimena, Czieso, Stephanie, Okoye, Isobel S., Rückerl, Dominik, Allen, Judith E., Brombacher, Frank, Wilson, Mark S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460998/ https://www.ncbi.nlm.nih.gov/pubmed/28507062 http://dx.doi.org/10.1084/jem.20161104

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