Tissue-resident T cells in hepatitis B: A new target for cure?

A hallmark of chronic hepatitis B virus (HBV) infection is the functional impairment and depletion of antiviral T cells. In this issue of JEM, Pallett et al. (https://doi.org/10.1084/jem.20162115) identify a reservoir of functional HBV-specific T cells among liver-resident T cells.

Detalles Bibliográficos
Autores principales: Bolte, Fabian J., Rehermann, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
News
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461010/
https://www.ncbi.nlm.nih.gov/pubmed/28526760
http://dx.doi.org/10.1084/jem.20170842
Descripción
Sumario:A hallmark of chronic hepatitis B virus (HBV) infection is the functional impairment and depletion of antiviral T cells. In this issue of JEM, Pallett et al. (https://doi.org/10.1084/jem.20162115) identify a reservoir of functional HBV-specific T cells among liver-resident T cells.

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