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TOG–tubulin binding specificity promotes microtubule dynamics and mitotic spindle formation
XMAP215, CLASP, and Crescerin use arrayed tubulin-binding tumor overexpressed gene (TOG) domains to modulate microtubule dynamics. We hypothesized that TOGs have distinct architectures and tubulin-binding properties that underlie each family’s ability to promote microtubule polymerization or pause....
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Rockefeller University Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461023/ https://www.ncbi.nlm.nih.gov/pubmed/28512144 http://dx.doi.org/10.1083/jcb.201610090 |