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A voltage-dependent K(+) channel in the lysosome is required for refilling lysosomal Ca(2+) stores
The resting membrane potential (Δψ) of the cell is negative on the cytosolic side and determined primarily by the plasma membrane’s selective permeability to K(+). We show that lysosomal Δψ is set by lysosomal membrane permeabilities to Na(+) and H(+), but not K(+), and is positive on the cytosolic...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461029/ https://www.ncbi.nlm.nih.gov/pubmed/28468834 http://dx.doi.org/10.1083/jcb.201612123 |