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Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones

Splicing is catalyzed by the spliceosome, a complex of five major small nuclear ribonucleoprotein particles (snRNPs). The pre-mRNA splicing factor PRPF8 is a crucial component of the U5 snRNP, and together with EFTUD2 and SNRNP200, it forms a central module of the spliceosome. Using quantitative pro...

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Detalles Bibliográficos
Autores principales:	Malinová, Anna, Cvačková, Zuzana, Matějů, Daniel, Hořejší, Zuzana, Abéza, Claire, Vandermoere, Franck, Bertrand, Edouard, Staněk, David, Verheggen, Céline
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461031/ https://www.ncbi.nlm.nih.gov/pubmed/28515276 http://dx.doi.org/10.1083/jcb.201701165

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