GOP-1: Helping phagosomes pass the acid test

Phagosomes form during engulfment of large particles and become increasingly acidic and proteolytic, ultimately fusing with lysosomes, in a process termed “phagosome maturation.” In this issue, Yin et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201610001) identify GOP-1 as essential for the...

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Detalles Bibliográficos
Autores principales: Stuart, Lynda M., Lacy-Hulbert, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461036/
https://www.ncbi.nlm.nih.gov/pubmed/28539387
http://dx.doi.org/10.1083/jcb.201704047
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author Stuart, Lynda M.
Lacy-Hulbert, Adam
author_facet Stuart, Lynda M.
Lacy-Hulbert, Adam
author_sort Stuart, Lynda M.
collection PubMed
description Phagosomes form during engulfment of large particles and become increasingly acidic and proteolytic, ultimately fusing with lysosomes, in a process termed “phagosome maturation.” In this issue, Yin et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201610001) identify GOP-1 as essential for the maturation of phagosomes containing apoptotic cells, through recruitment of the Rab GTPase UNC108.
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spelling pubmed-54610362017-12-05 GOP-1: Helping phagosomes pass the acid test Stuart, Lynda M. Lacy-Hulbert, Adam J Cell Biol Commentary Phagosomes form during engulfment of large particles and become increasingly acidic and proteolytic, ultimately fusing with lysosomes, in a process termed “phagosome maturation.” In this issue, Yin et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201610001) identify GOP-1 as essential for the maturation of phagosomes containing apoptotic cells, through recruitment of the Rab GTPase UNC108. The Rockefeller University Press 2017-06-05 /pmc/articles/PMC5461036/ /pubmed/28539387 http://dx.doi.org/10.1083/jcb.201704047 Text en © 2017 Stuart and Lacy-Hulbert http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentary
Stuart, Lynda M.
Lacy-Hulbert, Adam
GOP-1: Helping phagosomes pass the acid test
title GOP-1: Helping phagosomes pass the acid test
title_full GOP-1: Helping phagosomes pass the acid test
title_fullStr GOP-1: Helping phagosomes pass the acid test
title_full_unstemmed GOP-1: Helping phagosomes pass the acid test
title_short GOP-1: Helping phagosomes pass the acid test
title_sort gop-1: helping phagosomes pass the acid test
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461036/
https://www.ncbi.nlm.nih.gov/pubmed/28539387
http://dx.doi.org/10.1083/jcb.201704047
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